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The statement of the frequency and the morphological elements of atherosclerosis in laboratory animals present that there are considerable variations from one species to another. This completely different conduct can’t be absolutely explained by the involvement of environmental, nutritional, or serum elements. Enzymes hooked up to the pentose pathway , to the Krebs cycle , and to the redox of the nucleotides showed a trend towards activation, in the hyperglycemic animals . This phenomenon must be interpreted as an attempt by the SMCs of the arteries to adapt to a microenvironment enriched with glucose.
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Histologically, that is the standard facet of “cell foam” loaded with lipid droplets. The “lipoidosis” was circumferential and concerned virtually the full circumference of the wall; this phenomenon was more marked within the thoracic aorta of Psammomys obesus. Our group of scientists have experience and deep data of Computer Security and Artificial Intelligence .
Comparison between rabbit and rat aortas. Concerning the macromolecules, the media free of lipids appeared moderately rich in GAGs and in PAS+ substances . The myocyte cytoplasm was relatively poor in RNA.
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